Author

Jacob R. Leistico

University of Illinois Urbana-Champaign

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Assay:CITE-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

Jun S. SongiD· 3 shared Jeffrey B. ChengiD· 2 shared Raymond Jaihyun ChoiD· 2 shared Shuyi Zhang· 2 shared Alan LuuiD· 1 shared Christopher P. CookiD· 1 shared Somang Kim· 1 shared Timothy J. MilleriD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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3 shared papersBioinformatics

Jun S. SongORCID

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Author profile →

3 papers

Recent·Most cited

Spectral clustering of single-cell multi-omics data on multilayer graphs

Shuyi Zhang, Jacob R. Leistico, Raymond Jaihyun Cho, Jeffrey B. Cheng, Jun S. Song

This paper introduces two spectral clustering algorithms for multi-omic single-cell data and shows they produce results comparable to Seurat's WNN method on a CITE-seq dataset.

Bioinformatics · Jun 2, 2022Peer-reviewedBioinformatics

Predicting TCR-epitope Binding Specificity Using Deep Metric Learning and Multimodal Learning

Alan Luu, Jacob R. Leistico, Timothy J. Miller, Somang Kim, Jun S. Song

This paper predicts TCR-epitope binding specificity using deep metric learning and multimodal learning, revealing key amino acid patterns and challenging assumptions about physical proximity.

Genes · Apr 15, 2021Peer-reviewedBioinformatics

Riemannian geometry and statistical modeling correct for batch effects and control false discoveries in single-cell surface protein count data from CITE-seq

Shuyi Zhang, Jacob R. Leistico, Christopher P. Cook, Yale Liu, Raymond Jaihyun Cho, Jeffrey B. Cheng, Jun S. Song

Physical review. E · Jul 27, 2020Peer-reviewedBioinformatics