Author

Yale Liu

Icahn School of Medicine at Mount SinaiORCID 0000-0003-3936-1834Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alison GoateiD· 1 shared Chiara PediconeiD· 1 shared Christopher P. CookiD· 1 shared DA Pugh· 1 shared Jacob R. Leistico· 1 shared Jeffrey B. ChengiD· 1 shared Ji‐Long CheniD· 1 shared Jun S. SongiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Alison GoateORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 2, 2023

Development of MAPT S305 mutation models exhibiting elevated 4R tau expression, resulting in altered neuronal and astrocytic function

Kathryn R. Bowles, DA Pugh, Chiara Pedicone…·Alison Goate

This study develops isogenic iPSC lines with MAPT S305 mutations to increase 4R tau expression, revealing altered neuronal and astrocytic functions in tauopathies.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsPhysical review. EPeer-reviewedJul 27, 2020

Riemannian geometry and statistical modeling correct for batch effects and control false discoveries in single-cell surface protein count data from CITE-seq

Shuyi Zhang, Jacob R. Leistico, Christopher P. Cook…·Jun S. Song

1 citation

mousehuman

𝕏 PostBluesky