Author

Jacqueline A. M. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Abby Marquez· 1 shared Adrian L. Gill· 1 shared Carlos Stahlhut· 1 shared Christopher J. Schulze· 1 shared Christos Tzitzilonis· 1 shared Daphne Hsieh· 1 shared David Wildes· 1 shared Elena S. Koltun· 1 shared

Activity by Year

2017-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Abby Marquez

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1 paper

Recent·Most cited

Efficacy of SHP2 phosphatase inhibition in cancers with nucleotide-cycling oncogenic RAS, RAS-GTP dependent oncogenic BRAF and NF1 loss

Robert J. Nichols, Franziska Haderk, Carlos Stahlhut, Christopher J. Schulze, Golzar Hemmati, David Wildes, Christos Tzitzilonis, Kasia Mordec, Abby Marquez, Jason Romero, Daphne Hsieh, Gert Kiss, Elena S. Koltun, Adrian L. Gill, Mallika Singh, , Trever G. Bivona

This study shows that inhibiting SHP2 phosphatase effectively targets cancers driven by nucleotide-cycling RAS, RAS-GTP dependent BRAF, or NF1 loss by disrupting RAS-RAF-MEK-ERK signaling.

bioRxiv · Sep 14, 2017 · PreprintCancer Biology