YAP activation reverses aging-related visual dysfunction caused by impaired cell-matrix adhesion
Gyuri Kim, Chanok Son, Hyo Kyung Lee, Jaemyung Choi, Soomin Lee, Seyoun Oh, Jae‐Byoung Chae, Chul-Woo Park, Chaekyu Kim, Ja-Hyoung Ryu, Semin Lee, Jiwon Jang, Hyewon Chung
This study shows YAP activation reverses aging-related visual dysfunction in RPE cells by restoring cell-matrix adhesion, offering a potential therapeutic approach for AMD.
bioRxiv · Jan 8, 2026 · PreprintPhysiology