Ribosomal stress-induced senescence as a novel pro-senescence strategy for p16 positive basal-like breast cancer
Madeleine Moore, Luke Gammon, Sally Dreger, James Koh, James C Garbe, Martha R Stampfer, Michael Philpott, Louise Jones, Cleo L Bishop
This study identifies ribosomal proteins as pro-senescence targets in p16 positive basal-like breast cancer, showing their role in inducing stable cell cycle arrest and poor prognosis.
bioRxiv · Nov 14, 2018 · PreprintCancer Biology