Genome-Wide Fetalization of Enhancer Architecture in Heart Disease
Cailyn H. Spurrell, Iros Barozzi, Michael Kosicki, Brandon J. Mannion, Matthew J. Blow, Yoko Fukuda-Yuzawa, Neil Slaven, Sarah Yasmeen Afzal, Jennifer A. Akiyama, Veena Afzal, Stella Tran, Ingrid Plajzer-Frick, Catherine S. Novak, Momoe Kato, Elizabeth A. Lee, , Axel Visel
The paper identifies widespread epigenomic changes in idiopathic dilated cardiomyopathy, showing a shift toward fetal-like enhancer states and providing a data resource for further study.
Cell Reports · Sep 1, 2022Peer-reviewedGenomics