IGF-1 IMPACTS NEOCORTICAL INTERNEURON CONNECTIVITY IN EPILEPTIC SPASM GENERATION AND RESOLUTION
Carlos J. Ballester‐Rosado, John T. Le, Trang T. Lam, Anne E. Anderson, James D. Frost, John W. Swann
This study investigates how IGF-1 deficiencies affect neocortical interneurons and contribute to epileptic spasms, finding that restoring IGF-1 levels can rescue interneuron connectivity and reduce spasms.
Neurotherapeutics · Nov 8, 2024Peer-reviewedNeuroscience