Anne E. Anderson

The paper evaluates delta power abnormalities in a maternal UBE3A-deletion pig model of Angelman syndrome using EEG, finding elevated delta power during wakefulness and reduced transitions to sleep.

The paper examines factors influencing task-based research participation in pediatric epilepsy patients undergoing sEEG, finding that comorbidities do not typically prevent participation.

The paper shows that human auditory cortex preferentially tracks speech over music in children and adolescents without explicit attention, with speech-bias strengthening in the superior temporal gyrus with age.

This paper describes a pig model of Angelman syndrome that mirrors early developmental symptoms observed in humans.

This study investigates how IGF-1 deficiencies affect neocortical interneurons and contribute to epileptic spasms, finding that restoring IGF-1 levels can rescue interneuron connectivity and reduce spasms.

The paper investigates how auditory responses are modulated during speech production by analyzing intracranial EEG data from patients with epilepsy.

This study shows that Shox2 is essential for maintaining thalamic spindle function by regulating firing properties of thalamocortical neurons, leading to impaired sleep spindles and related behaviors.

This paper describes the development of an antisense oligonucleotide (ASO) therapy targeting the UBE3A-AS transcript to reactivate paternal UBE3A expression in Angelman syndrome models.

This study identifies 69 mutated genes in malformations of cortical development using multiomic profiling of 317 brain resections and single-cell sequencing.

This study shows that increasing 4E-BP1 activity in juvenile mice with FMCD reduces neuronal dysfunction and seizures by correcting electrophysiological and structural abnormalities.