Assembling Large Genomes with Single-Molecule Sequencing and Locality Sensitive Hashing
Konstantin Berlin, Sergey Koren, Chen-Shan Chin, James Drake, Jane M Landolin, Adam M Phillippy
The paper introduces MHAP, a method using locality-sensitive hashing to improve genome assembly from single-molecule sequencing, achieving high-quality assemblies for multiple organisms.
Nature Biotechnology · May 25, 2015Peer-reviewedBioinformatics