Microglial P2Y12 mediates chronic stress-induced synapse loss in the prefrontal cortex and associated behavioral consequences in male mice
Justin L. Bollinger, David T. Dadosky, James K. Flurer, Ivanka L. Rainer, Samuel C. Woodburn, Eric S. Wohleb
This study shows that blocking P2Y12 in microglia prevents stress-induced synapse loss and behavioral deficits in male mice.
bioRxiv · Mar 16, 2022 · PreprintNeuroscience