Samuel C. Woodburn

This study shows that microglial BDNF is essential for ketamine's antidepressant and synaptogenic effects in the prefrontal cortex.

This study shows psilocybin increases dendritic spine density and improves fear extinction in chronically stressed mice.

This study identifies specific pyramidal cell types and 5-HT2A receptors in the medial frontal cortex as essential for psilocybin's long-term therapeutic effects.

This study investigates how psilocybin affects fear extinction in mice, finding that dose, context, and serotonin receptors are critical factors.

This study investigates the behavioral and neural effects of 5-MeO-DMT in mice, showing dose-dependent changes in behavior and long-term dendritic spine density increases without affecting spine size.

This study shows that blocking P2Y12 in microglia prevents stress-induced synapse loss and behavioral deficits in male mice.