The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration
Paymaan Jafar‐Nejad, Berit E. Powers, Armand Soriano, Hien Tran Zhao, Daniel A Norris, John E. Matson, Bea DeBrosse-Serra, Jamie Watson, Padmakumar Narayanan, Seung Joo Chun, Curt Mazur, Holly B. Kordasiewicz, Eric E. Swayze, Frank Rigo
The paper maps ASO distribution and activity in the CNS of rodents and NHP after central administration, showing widespread effects across cell types.
Nucleic Acids Research · Dec 22, 2020Peer-reviewedNeuroscience