SGLT2 inhibition by intraperitoneal dapagliflozin mitigates peritoneal fibrosis and ultrafiltration failure in a mouse model of chronic peritoneal exposure to high-glucose dialysate
Michael S. Balzer, Song Rong, Johannes Nordlohne, Jan D. Zemtsovski, Sonja Schmidt, Britta Stapel, Maria Bartosova, Sibylle von Vietinghoff, Hermann G. Haller, Claus Peter Schmitt, Nelli Shushakova
This study shows that dapagliflozin reduces peritoneal fibrosis and improves ultrafiltration in a mouse model of high-glucose peritoneal dialysis.
Biomolecules · Nov 19, 2020Peer-reviewedMolecular Biology