Author

Michael S. Balzer

University of PennsylvaniaORCID 0000-0003-0508-1260Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Hongbo LiuiD· 2 shared Katalin SusztákiD· 2 shared Klaus H. KaestneriD· 2 shared Rojesh ShresthaiD· 2 shared Ziyuan MaiD· 2 shared Amin AbediniiD· 1 shared Amy KwaniD· 1 shared Anil K. KarihalooiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenetics

Hongbo LiuORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintOct 24, 2022

Spatially resolved human kidney multi-omics single cell atlas highlights the key role of the fibrotic microenvironment in kidney disease progression

Amin Abedini, Jonathan L. Levinsohn, Konstantin A. Klötzer…·Katalin Suszták

Multi-omic and spatial profiling of 81 human kidney samples resolves four tissue microenvironments; the fibrotic one's gene signature is reported to beat histopathology at predicting outcome.

43 citations

humanscRNA-seq

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Developmental BiologyNature CommunicationsPeer-reviewedApr 15, 2021

Single cell resolution regulatory landscape of the mouse kidney highlights cellular differentiation programs and renal disease targets

Zhen Miao, Michael S. Balzer, Ziyuan Ma…·Katalin Suszták

The paper maps the regulatory landscape of the mouse kidney at single cell resolution, identifying key transcription factors and regulatory circuits, and linking variants to kidney disease.

209 citationstop 1%

mousescATAC-seq

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Molecular BiologyBiomoleculesPeer-reviewedNov 19, 2020

SGLT2 inhibition by intraperitoneal dapagliflozin mitigates peritoneal fibrosis and ultrafiltration failure in a mouse model of chronic peritoneal exposure to high-glucose dialysate

Michael S. Balzer, Song Rong, Johannes Nordlohne…·Nelli Shushakova

This study shows that dapagliflozin reduces peritoneal fibrosis and improves ultrafiltration in a mouse model of high-glucose peritoneal dialysis.

67 citationstop 4%

mouseexperimental assay

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