Author

Jan Lukas Kleiner

University of Bonn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Christina Katharina WeisheitiD· 1 shared Frank SplettstoesseriD· 1 shared Jimmy ZhengiD· 1 shared Mark CoburniD· 1 shared Mark E. PepiniD· 1 shared Sebastian ZimmeriD· 1 shared Stilla FredeiD· 1 shared Yunyang ZhangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperMolecular Biology

Christina Katharina WeisheitORCID

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Author profile →

1 paper

Recent·Most cited

Aortic valve stenosis promotes pathological shear stress-dependent epigenomic dysregulation in circulating T cells.

Yunyang Zhang, Jan Lukas Kleiner, Jimmy Zheng, Frank Splettstoesser, Sebastian Zimmer, Mark Coburn, Christina Katharina Weisheit, Stilla Frede, Mark E. Pepin

This study identifies epigenomic changes in circulating T cells associated with aortic valve stenosis, showing a methylation risk score correlates with hemodynamic severity.

bioRxiv · May 19, 2026 · PreprintMolecular Biology