Improved optogenetic modification of the spiral ganglion neurons for future optical cochlear implants
Anupriya Thirumalai, Jana Henseler, Marzieh Enayati, Kathrin Kusch, Roland Hessler, Tobias Moser, Antoine Tarquin Huet
This study improves optogenetic modification of spiral ganglion neurons in gerbils using microcatheter-based AAV delivery, achieving reliable ChR expression in 80% of treated animals but with limited transduction efficiency.
Theranostics · Mar 18, 2025Peer-reviewedNeuroscience