Kathrin Kusch

This paper demonstrates that multichannel optical cochlear implants (oCIs) with ChReef enable improved spectral resolution compared to electrical stimulation in gerbils.

CochleaNet is a deep learning framework for analyzing cochlea imaging data, enabling segmentation and analysis of cochlear structures and gene therapy products.

This study identifies Paralemmin-3 as a critical protein for maintaining the structural integrity of the lateral wall in auditory hair cells, with its loss causing hearing impairment and structural collapse.

This study improves optogenetic modification of spiral ganglion neurons in gerbils using microcatheter-based AAV delivery, achieving reliable ChR expression in 80% of treated animals but with limited transduction efficiency.

The paper develops a correlative cryo-light/electron microscopy workflow to target and image synapses with cryo-ET, revealing excitatory synapses.

This study shows that CaBP1 and CaBP2 suppress CaV1.3 channel inactivation in inner hair cells, enabling sustained synaptic transmission and hearing.

The paper shows that myelin acts as an energy reserve in the brain under glucose deprivation, supporting oligodendrocytes and axons through fatty acid oxidation.

This study shows that oligodendrocytes contribute to sustained stimulus perception in complex auditory tasks, beyond their role in increasing axonal conduction velocity.

This study shows that continuous myelin synthesis is necessary for maintaining white matter integrity, as preventing new myelin formation in adult mice leads to myelin degradation and neurological disease.