GenomicsbioRxiv
Single-molecule sequencing and conformational capture enable de novo mammalian reference genomes
Derek M Bickhart, Benjamin D Rosen, Sergey Koren…·Timothy P.L. Smith
This paper presents a de novo mammalian genome assembly for the domestic goat using long-read sequencing, short-read validation, and chromatin interaction mapping, achieving high contiguity and resolving repetitive regions.
DOI 10.1038/ng.3802