Specific exclusion of conjugative plasmids from the gut microflora
Muhammad Kamruzzaman, Alma Y. Wu, Janani Jeyachandran, Jonathan R. Iredell
The paper engineers a probiotic plasmid using exclusion genes from AMR plasmids to block their spread in the gut, showing effectiveness in vitro and in mice.
bioRxiv · Aug 27, 2026 · PreprintMicrobiology