Overmaturation as a major trajectory of naive CD4 T cell aging
CJ Kelly, Janessa Wagandi, Danny Quaranta, Dina M. Prosser, Morgan Diegel, Nikolay Burnaevskiy
This study identifies transcriptional overmaturation as a key trajectory in naive CD4 T cell aging, showing aging-related changes mirror normal maturation processes.
bioRxiv · Feb 5, 2026 · PreprintCell Biology