Author

Morgan Diegel

Altius Institute for Biomedical Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:ChIP-seq· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

John A. StamatoyannopoulosiD· 4 shared Kristen LeeiD· 4 shared Rajinder KauliD· 4 shared Alex P. ReynoldsiD· 3 shared Daniel BatesiD· 3 shared Douglas Dunn· 3 shared Eric HaugeniD· 3 shared Eric RynesiD· 3 shared

Activity by Year

2018-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

John A. StamatoyannopoulosORCID

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5 papers

Recent·Most cited

Overmaturation as a major trajectory of naive CD4 T cell aging

CJ Kelly, Janessa Wagandi, Danny Quaranta, Dina M. Prosser, Morgan Diegel, Nikolay Burnaevskiy

This study identifies transcriptional overmaturation as a key trajectory in naive CD4 T cell aging, showing aging-related changes mirror normal maturation processes.

bioRxiv · Feb 5, 2026 · PreprintCell Biology

Index and biological spectrum of accessible DNA elements in the human genome

Wouter R. A. Meuleman, Alexander Muratov, Eric Rynes, Jessica M. Halow, Kristen Lee, Daniel Bates, Morgan Diegel, Douglas Dunn, Fidencio Jun Neri, Athanasios Teodosiadis, Alex P. Reynolds, Eric Haugen, Jemma S. Nelson, Audra Johnson, Mark Frerker, , John A. Stamatoyannopoulos

The paper creates high-precision maps of DNase I hypersensitive sites across 733 human biosamples and develops a regulatory vocabulary to annotate regulatory DNA, concentrating disease-associated signals.

Nature · Jul 29, 2020Peer-reviewedGenomics

Global reference mapping and dynamics of human transcription factor footprints

Jeff D. Vierstra, John E. Lazar, Richard S. Sandstrom, Jessica M. Halow, Kristen Lee, Daniel Bates, Morgan Diegel, Douglas Dunn, Fidencio Jun Neri, Eric Haugen, Eric Rynes, Alex P. Reynolds, Jemma S. Nelson, Audra Johnson, Mark Frerker, , John A. Stamatoyannopoulos

The paper maps transcription factor footprints across 243 human cell and tissue types, revealing their structure, function, and relationship to genetic variation and disease.

Nature · Jul 29, 2020Peer-reviewedGenomics

Atlas and developmental dynamics of mouse DNase I hypersensitive sites

Charles E. Breeze, John E. Lazar, Tim R. Mercer, Jessica M. Halow, Ida W. Smoak, Kristen Lee, Sean Ibarrientos, Andrés Castillo, Fidencio Jun Neri, Eric Haugen, Eric Rynes, Alex P. Reynolds, Daniel Bates, Morgan Diegel, Douglas Dunn, , John A. Stamatoyannopoulos

The paper creates a mouse regulatory DNA atlas by mapping DNase I hypersensitive sites across development and shows dynamic changes in regulatory elements and transcription factor activity.

bioRxiv · Jun 26, 2020 · PreprintGenomics

An Integrative Framework For Detecting Structural Variations In Cancer Genomes

Jesse R. Dixon, Jie Xu, Vishnu Dileep, Ye Zhan, Fan Song, Victoria T. Le, Galip Gürkan Yardımcı, Abhijit Chakraborty, Darrin V. Bann, Yanli Wang, Royden A. Clark, Lijun Zhang, Hongbo Yang, Tingting Liu, Sriranga Iyyanki, , Feng Yue

This paper presents an integrative framework to detect structural variants in cancer genomes using multiple methods and finds that non-coding structural variation significantly impacts genome function in cancer cells.

Nature Genetics · Sep 4, 2018Peer-reviewedGenomics