Glomerular Endothelial Cell-Derived Extracellular Vesicles Cross the Basement Membrane to Regulate Podocyte Function
Janina Kern, Sindhu Thiagarajan, Nina Sopel, Alexandra Ohs, Patricia Luckner, Astrid Bruckmann, Jan Van Deun, Mustafa Kocademir, George Sarau, Silke Christiansen, Christoph Daniel, Mario Schiffer, Stefan Uderhardt, Janina Müller‐Deile
This study shows glomerular endothelial cell-derived extracellular vesicles cross the basement membrane and regulate podocyte function through miR-mediated gene repression and protease activity.
bioRxiv · Jan 30, 2026 · PreprintPhysiology