A quantitative modular modeling approach reveals the consequences of different A20 feedback implementations for the NF-kB signaling dynamics
Janina Mothes, Inbal Ipenberg, Seda Çöl Arslan, Uwe Benary, Claus Scheidereit, Jana Wolf
The paper compares different A20 feedback implementations in NF-κB signaling models to determine their impact on dynamics, finding that one model aligns with experimental data.
Frontiers in Physiology · Jul 28, 2020Peer-reviewedSystems Biology