Author

Jannik Wempe

Technische Universität Darmstadt

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Neuroscience· 1

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Approach:experimental assay· 1

Frequent Co-Authors

Adriana Müller-Längle· 1 shared Bodo LaubeiD· 1 shared Kai LangeriD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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1 shared paperNeuroscience

Adriana Müller-Längle

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1 paper

Recent·Most cited

Analysis of M4 transmembrane domains in NMDA receptor function: a negative allosteric modulation site at the GluN1 M4 is determining the efficiency of neurosteroid modulation

Kai Langer, Adriana Müller-Längle, Jannik Wempe, Bodo Laube

This study investigates the role of the M4 transmembrane domain in NMDA receptor function, showing that its deletion leads to nonfunctional receptors, but functional rescue is possible with isolated M4 peptides, and that M4 interfaces are critical for neurosteroid modulation.

Frontiers in Pharmacology · Oct 1, 2021Peer-reviewedNeuroscience