The P2X7 receptor is an intermediate in the retinoic acid-signaling pathway that induces neuronal remodeling in retinitis pigmentosa
Michael Telias, Leonor Afrima, Jared Endres, Bristol Denlinger, Richard Krämer
This paper identifies the P2X7 receptor as an intermediary in RA signaling that induces neuronal remodeling in retinitis pigmentosa, showing its role in RGC hyperactivity and hyperpermeability.
bioRxiv · May 31, 2026 · PreprintNeuroscience