Richard Krämer

The paper introduces Tension TRAAKer, a chemigenetic fluorescent membrane tension reporter that visualizes tension dynamics in living cells with high spatiotemporal precision.

This paper identifies the P2X7 receptor as an intermediary in RA signaling that induces neuronal remodeling in retinitis pigmentosa, showing its role in RGC hyperactivity and hyperpermeability.

The paper introduces three genetically encoded tools to specifically ablate excitatory and inhibitory synapses using E3 ligase-dependent degradation mechanisms.

The paper shows that retinoic acid receptor inhibition restores synaptic function in bipolar cells of RP models, improving visual signal transmission.

The paper shows that On-cone bipolar cells use NaV channels from coupled amacrine cells to enhance signal transmission in dim light.

This study investigates Magnetogenetics' ability to control neuronal bioelectrical properties using ferritin-based FeRIC constructs, showing RF-induced depolarization and hyperpolarization effects.

This study uses adaptive optical two-photon fluorescence microscopy to investigate retinal microvascular and neuronal pathologies in vivo, revealing microvascular lesions and pharmacological effects.

The paper shows that inhibiting retinoic acid (RA) reduces retinal ganglion cell (RGC) hyperactivity and improves image detection in a mouse model of retinal degeneration.

This study shows that somatic nicotinic acetylcholine receptors in VTA dopamine neurons modulate firing properties and reward-related behaviors through optical manipulation.