POGZ safeguards neuronal gene chromatin architecture and transcription
Natasha Ann Mariano, Katerina J. Williams, Katie Munechika, Katherine M. Bonefas, Yu Sun, Weiyu Zhang, Jared L. Klein, Kevin D. Monahan, Haiyuan Yu, Cedric Feschotte, Eirene Markenscoff-Papadimitriou
This paper investigates the role of POGZ in maintaining chromatin architecture and transcription in the developing mouse cortex, finding that its loss disrupts H3K9me3 distribution and impairs neuronal gene expression.
bioRxiv · Jul 3, 2026 · PreprintNeuroscience