Eirene Markenscoff-Papadimitriou

This study identifies a cell-type-specific transcriptional response in rNTS neurons to fasting, showing downregulation of Gabrd in excitatory neurons.

This paper investigates the role of POGZ in maintaining chromatin architecture and transcription in the developing mouse cortex, finding that its loss disrupts H3K9me3 distribution and impairs neuronal gene expression.

This study identifies araucan as a transcription factor that regulates butterfly wing iridescence by coordinating scale structure and pigmentation through pattern-specific effects.

The paper identifies 21 human 'lonely genes' in large gene deserts, finds they are mostly cell adhesion molecules, and suggests they are structurally isolated and vulnerable in brain development.

The paper identifies ivory, a conserved lncRNA, as the color pattern gene at the cortex locus in buckeye butterflies, showing how cis-regulatory elements of ivory influence seasonal color variation.

The paper identifies shared regulatory targets of autism-associated transcriptional regulators in brain-expressed genes and shows their functional convergence in neurodevelopmental outcomes.

The paper shows POGZ promotes chromatin accessibility and expression of synaptic genes in mouse and human brains, and its reduction disrupts cortical function through interactions with ADNP.

The paper creates a chromatin accessibility atlas of the developing human telencephalon to identify regulatory elements and their role in gene expression and neurodevelopmental disorders.

This study examines the role of noncoding variation in autism spectrum disorder using whole genome sequencing of 2,076 genomes, finding no significant association after correction for multiple testing.