Early-life Exposure to Arsenic Primes the Offspring to Increased Asthma Risk: Transcriptome and Epigenome Analysis
Yuchen Sun, Musa Watfa, Qinying Sun, Dhivyaa Rajasundaram, Ben Schlegel, Hoi-yee. Yeung, Jarius Pulczinski, Bong Soo Park, Aaron Barchowsky, Wayne Mitzner, Shyam S. Biswal, Wan‐Yee Tang
This study shows that maternal exposure to low-level inorganic arsenic increases offspring asthma risk through epigenetic changes, including miR-101c downregulation and TGFβ pathway dysregulation.
bioRxiv · Aug 1, 2025 · PreprintGenomics