Shyam S. Biswal

This study shows perinatal exposure to heavy metals and their mixtures alters cardiac gene expression, cellular composition, and immune signaling in a sex-specific manner in mice.

Perinatal exposure of mice to a Pb, As, Cd and Cr(VI) mixture at EPA levels impaired recognition memory, raised anxiety-like behavior, and altered mPFC neuron function.

This study shows that maternal exposure to low-level inorganic arsenic increases offspring asthma risk through epigenetic changes, including miR-101c downregulation and TGFβ pathway dysregulation.

The paper shows early-life toxicant exposure reprograms epigenomic aging, altering gene expression in liver cells and disease risk in adulthood.

The paper establishes a database of lung cancer mouse models to improve data comparison and translational relevance by aligning mouse mutations with human lung cancer mutations.

This study creates a rat model with SYNGAP enzymatic domain deletion, showing learning, social, and seizure deficits in heterozygous animals.