Perinatal Exposure to Organophosphate Flame Retardants Induces Sex- and Hormone-Dependent Alterations in Anxiety, Memory, Neurotransmitter Content, and Hippocampal Gene Expression
Kimberly Wiersielis, Kevin M. Moran, RidhaFatima Mukadam, Jarrett Early, Vicki Appel, Catherine M. Rojas, Ali Yasrebi, Thomas DeGroat, Nadja Knox, Troy Adam Roepke
This study shows that perinatal exposure to OPFRs causes sex- and hormone-dependent changes in behavior, neurochemistry, and gene expression in adult mice.
bioRxiv · Jan 23, 2026 · PreprintPharmacology & Toxicology