The extracellular matrix differentially directs myoblast motility in distinct forms of muscular dystrophy
Ashlee M. Long, Jason M. Kwon, GaHyun Lee, Nina L. Reiser, Lauren A. Vaught, Joseph G. O’Brien, Patrick Page, Michele Hadhazy, Joseph C. Reynolds, Rachelle H. Crosbie, Alexis R. Demonbreun, Elizabeth M. McNally
The paper shows that different forms of muscular dystrophy have distinct ECM compositions that affect myoblast motility, with annexin A6 playing a key role in enhancing movement.
bioRxiv · Oct 31, 2022 · PreprintMolecular Biology