A dynamic metabolic flux analysis (DMFA) model for performance predictions of diverse CHO cell culture process modes and conditions
Jayanth Venkatarama Reddy, Nikola G. Malinov, Jason Souvaliotis, Eleftherios Terry Papoutsakis, Marianthi Ierapetritou
The paper develops a DMFA model to predict CHO cell culture performance under various conditions and validates its predictions experimentally.
bioRxiv · Jan 12, 2026 · PreprintBioengineering