Redox regulation of neuroinflammatory pathways contributes to damage in Alzheimers disease brain
Lauren N. Carnevale, Piu Banerjee, Xu Zhang, Jazmin Navarro, Charlene K Raspur, Parth R. Patel, Tomohiro Nakamura, Emily Schahrer, Henry R. Scott, Nhi Lang, Jolene K. Diedrich, Amanda J. Roberts, John R. Yates, Stuart A. Lipton
The paper identifies S-nitrosylation of STING as a redox modification driving aberrant cGAS-STING signaling in Alzheimer's disease, contributing to neuroinflammation and synaptic loss.
Cell chemical biology · Apr 23, 2026Peer-reviewedNeuroscience