Starting strong: A descending analgesic dosing scheme enhances pain relief compared to a conventional ascending dosing scheme
Marilyn Mintah, Jean Daunizeau, Alexandra Tinnermann
This study compares descending and ascending analgesic dosing schemes, finding that starting with a high dose enhances placebo-related pain relief compared to starting with a low dose.
bioRxiv · Oct 16, 2026 · PreprintNeuroscience