Alexandra Tinnermann

Starting strong: A descending analgesic dosing scheme enhances pain relief compared to a conventional ascending dosing scheme

This study compares descending and ascending analgesic dosing schemes, finding that starting with a high dose enhances placebo-related pain relief compared to starting with a low dose.

Conditioned pain modulation recruits the descending pain modulatory system to inhibit spinal activity

This study uses fMRI to show that conditioned pain modulation involves reduced spinal activity and increased descending pain modulation during pain suppression in humans.

EPISeg: Automated segmentation of the spinal cord on echo planar images using open-access multi-center data

The paper introduces EPISeg, a deep learning model for automated spinal cord segmentation on gradient-echo EPI data, showing improved performance over existing methods.

Body size interacts with the structure of the central nervous system: A multi-center in vivo neuroimaging study

This study shows body size parameters significantly correlate with brain and spinal cord MRI metrics and should be included in neuroimaging studies.

Ventral premotor cortex influences spinal cord activation during force generation

Cortico-spinal coupling along descending pain system differentiates between opioid and saline treatment in healthy participants

This study examines how opioid treatment affects cortico-spinal coupling in the pain system, showing stronger coupling in those with greater analgesia compared to saline control.