Strength in Unity: a Dual Strategy to Restore NK Cell Cytotoxicity against Pancreatic Ductal Adenocarcinoma
Camille Rolin, Aubin Pitiot, Gilles Iserentant, Anaïs Oudin, Jean-Yves Servais, Victoria El‐Khoury, Vanessa Barthelemy, Céline Hoffmann, Anna Golebiewska, Yong-Jun Kwon, Jacques Zimmer, Carole Seguin‐Devaux
This study develops and tests a dual strategy using NaMiX and TriKE to enhance NK cell cytotoxicity against PDAC, showing improved tumor cell killing in vitro and in humanized mouse models.
bioRxiv · Feb 11, 2026 · PreprintImmunology