Inhibition of HIV-1 gene transcription by KAP1 in myeloid lineage
Amina Aït-Ammar, Maxime Bellefroid, Fadoua Daouad, Valérie Martinelli, Jeanne Van Assche, Clémentine Wallet, Anthony Rodari, Marco De Rovere, Birthe Fahrenkrog, Christian Schwartz, Carine M. Van Lint, Virginie Gautier, Olivier Rohr
This study shows that KAP1 represses HIV-1 gene expression in myeloid cells by interacting with Tat and CTIP2, contributing to HIV-1 latency.
Scientific Reports · Jan 29, 2021Peer-reviewedMolecular Biology