Loss of asgr1a leads to the secretion of excess dietary cholesterol in zebrafish
Joshua T. Derrick, Tabea O. C. Moll, Darby W. Sweeney, Jeffrey Shin, Monika Svecla, Giuseppe Danilo Norata, Steven Arthur Farber
This study shows that loss of asgr1a in zebrafish leads to excess dietary cholesterol excretion rather than hepatic accumulation, suggesting a role for ASGR1 in cholesterol metabolism.
Journal of Biological Chemistry · Jun 9, 2026Peer-reviewedPathology