NeurosciencebioRxivPreprint
α-Synuclein Activates the PI3K/AKT Pathway to Drive Lipid Droplets Accumulation: Implications for Parkinson's Disease
Suaad Abd Elhadi, Jenna Congdon-Loeffler, Eva Harrosch…·Ronit Sharon
This study shows that α-synuclein activates the PI3K/AKT pathway, leading to lipid droplet accumulation in Parkinson's disease, and suggests PI3K inhibition as a therapeutic strategy.
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