Author

Jennifer Klimek

University of Cologne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Organism:mouse· 1

Frequent Co-Authors

Hans ZempeliD· 3 shared M. BelliD· 2 shared Sarah Bachmann· 2 shared Daniel Adam· 1 shared Felix LangerscheidtiD· 1 shared Laura Köhler· 1 shared Mohamed Aghyad Al KabbaniiD· 1 shared Tamara Wied· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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3 shared papersNeuroscience

Hans ZempelORCID

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3 papers

Recent·Most cited

Knockdown of TTLL1 reduces Aβ-induced TAU pathology in human iPSC-derived cortical neurons

Mohamed Aghyad Al Kabbani, Laura Köhler, Tamara Wied, Daniel Adam, Jennifer Klimek, Hans Zempel

This study shows that knocking down TTLL1 reduces Aβ-induced TAU pathology and microtubule dysfunction in human iPSC-derived neurons.

bioRxiv · Nov 19, 2024 · PreprintNeuroscience

Axonal TAU sorting requires the C-terminus of TAU but is independent of ANKG and TRIM46 enrichment at the AIS

M. Bell, Sarah Bachmann, Jennifer Klimek, Felix Langerscheidt, Hans Zempel

This study shows that SH-SY5Y-derived neurons can efficiently sort axonal TAU, requiring the C-terminus but not ANKG or TRIM46 at the AIS.

Neuroscience · Feb 6, 2021Peer-reviewedNeuroscience

Differential effects of human TAU isoforms: Somatic retention of 2N-TAU and increased microtubule number induced by 4R-TAU

Sarah Bachmann, M. Bell, Jennifer Klimek, Hans Zempel

This study examines the subcellular localization and effects of different human TAU isoforms on cell size and microtubule dynamics in neuroblastoma cells.

bioRxiv · Jun 16, 2020 · PreprintNeuroscience