iPSC-Derived Myotubes from ME/CFS Patients Reveal Signature Genes, Isoforms and Pathways with Drug Repurposing Potential
Dao Nguyen, Trang T. T. Truong, Bruna Panizzutti, Megan Ellis, Briana Spolding, Courtney Swinton, Chiara C. Bortolasci, Jenny Bryce, Jess Smith, Cassie Field, Zoe Shih-Jung Liu, Jee Hyun Kim, Michael Berk, Ken R. Walder
The paper uses iPSC-derived myotubes from ME/CFS patients and controls to identify differentially expressed genes, isoforms, and pathways, and prioritizes compounds for drug repurposing.
bioRxiv · Oct 7, 2026 · PreprintCell Biology