Deep learning-guided design of cell type-specific AAV promoters
Sean K. Wang, Boxiong Deng, Surag Nair, 任肖白, Jiaying Li, J Tijerina, Praveen Prakhar, Ziming Luo, Chelsea Nnebe, Samuel H. Kim, Yimin Zhou, Sahil Hemant Shah, Alexander Davis, Rohan Mahajan, Yilin Qiao, , Sui Wang
This study designs cell type-specific AAV promoters using deep learning, outperforming rational approaches in mouse retinal cells and showing promise for human applications.
bioRxiv · Jan 14, 2026 · PreprintSynthetic Biology