Sahil Hemant Shah

This study designs cell type-specific AAV promoters using deep learning, outperforming rational approaches in mouse retinal cells and showing promise for human applications.

This study identifies OPTN's role in axonal mitochondria transport and shows its loss contributes to neurodegeneration in models of ALS and NTG.

The paper shows that Mettl14-mediated m6A modification is critical for cell cycle progression of late-born retinal progenitor cells, preventing cell cycle arrest and neuronal death.

The paper shows that light-evoked activity and BDNF regulate mitochondrial dynamics and localized translation in axons during retinal ganglion cell maturation.