Building an atlas of mechanobiology: high-throughput contractility screen of 2418 kinase inhibitors in five primary human cell types reveals selective divergent responses among related cell types
Anton Shpak, Jeremy Wan, Ricky Huang, Enrico Cortes, Yao Wang, Robert D. Damoiseaux, Ivan Pushkarsky
The paper screens 2,418 kinase inhibitors across five human cell types to identify cell-type specific contractility responses and challenges assumptions about pathway conservation.
bioRxiv · Jan 11, 2025 · PreprintBioengineering