Determining subpopulation methylation profiles from bisulfite sequencing data of heterogeneous samples using DXM
Jerry Fong, Jacob R. Gardner, Jared M. Andrews, Amanda F. Cashen, Jacqueline E. Payton, Kilian Q. Weinberger, John R. Edwards
DXM deconvolves methylation profiles of subpopulations from heterogeneous bisulfite sequencing data, showing improved performance over existing methods and linking methylation to relapse in DLBCLs.
Nucleic Acids Research · Jun 4, 2021Peer-reviewedBioinformatics