The evolution lifecycle of ribosome hibernation factors
Lewis I. Chan, Kimiho Omae, Charlotte R. Brown, Kazuaki Amikura, Chinenye L. Ekemezie, Jessica Clark, Kenji Nishide, Karla Helena-Bueno, Paweł Palmowski, Andrew Porter, Shino Suzuki, Sergey V. Melnikov
The paper analyzes 46,015 bacterial genomes to show hibernation factors evolved from large proteins, reduced in size, and were lost in over 10% of species, with some bacteria borrowing factors from others.
bioRxiv · Nov 4, 2025 · PreprintMicrobiology