LEO1 loss promotes ER stress-adapted migration and cholesterol dependency in colorectal cancer
Su Chan Park, Ji-Yeon Lee, So Hyun Kwon, Eun Jung Park, Ji Min Lee
This study shows that LEO1 loss in colorectal cancer promotes ER stress-adapted migration and cholesterol dependency, suggesting therapeutic targets for metastatic LEO1-low CRC.
bioRxiv · May 20, 2026 · PreprintCancer Biology