PRMT7 mediated PTEN activation promotes bone formation in female mice
Yingfei Zhang, Jia Qing, Li Yang, Xin Gao, Dazhuang Lu, Yiyang Wang, Lanxin Gu, Hui Zhang, Zechuan Li, Xu Wang, Yongsheng Zhou, Ping Zhang
This study identifies PRMT7 as an epigenetic regulator of bone formation in female mice, showing it activates PTEN to promote osteogenesis, with no effect in males.
bioRxiv · Jul 31, 2024 · PreprintDevelopmental Biology