Hantaan virus-derived peptides that stabilize HLA-E could abrogate inhibition of CD56dimNKG2A+ NK cells
Manling Xue, Kang Tang, Yusi Zhang, Xiaoyue Xu, Chunmei Zhang, Jiajia Zuo, Fenglan Wang, Xiyue Zhang, Xuyang Zheng, Ran Zhuang, Yun Zhang, Boquan Jin, Ying Ma
This study identifies HTNV-derived peptides that stabilize HLA-E, abrogating inhibition of CD56dimNKG2A+ NK cells and enhancing antiviral immune responses in HFRS.
PLoS Pathogens · Jul 18, 2025Peer-reviewedImmunology